Cosyntropin: track every shot, units to draw and what's still active

Synthetic ACTH (1-24) branded as Cortrosyn; used clinically for adrenal function testing (ACTH stimulation test). In the Peppy catalog, Cosyntropin is reconstituted from a vial and drawn up in units on an insulin syringe, dosed in mcg, typically as needed, with a listed half-life of about 15 minutes.

CategoryHormonal
FormVial (reconstitute)
Dose unitmcg
Typical frequencyAs needed
Half-life (catalog)~15 minutes
Also known asCortrosyn, Tetracosactide, ACTH (1-24)

Cosyntropin reconstitution calculator

Cosyntropin reconstitution calculator

Free in the app
10units
to draw on a U-100 insulin syringe · 0.1 mL
0102030405060708090100
Concentration2.5 mg/mL
Per unit25 mcg
Doses per vial20
Mathematical conversion only. Always verify with your prescriber. Cosyntropin tracker page → Save it in Peppy

How long Cosyntropin stays active

Active in your system — Cosyntropin

estimate for one dose, half-life 0.25 h
0hpeak0
Half-life ~15 minutes~5 half-lives to clear most of a dose 1.2 hours

An estimate from the half-life, not a measurement. Individual clearance varies. Peppy shows this curve for each protocol under Active in your system.

Cosyntropin dose steps in the catalog

Cosyntropin — catalog dose ladderDose
Step 1250 mcg

Dose steps as listed in the Peppy catalog so the picker is fast — not a recommendation. Your prescriber sets your dose; Peppy tracks it.

How to track Cosyntropin in Peppy

  1. Open the Protocols tab, tap + and search for Cosyntropin (or Cortrosyn). Form, unit and typical frequency are prefilled.
  2. Enter your vial size, the water you added and your dose. The inline Calculator shows the units to draw and warns if it will not fit a 1 mL syringe.
  3. Pick a colour and, for injections, a site rotation order. Peppy suggests the next site each time you log.
  4. On shot day, the Today tab counts down and one tap opens the Log shot sheet with the body map.
  5. Open the protocol to see Active in your system, the half-life curve for what you have logged (Pro).
  6. Log a daily check-in (side effects, feelings, weight) and see it lined up against every dose in Progress.

Track Cosyntropin in Peppy

Schedule, units, site rotation and reminders. Free on iPhone, no account.

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Frequently asked

How many units is 250 mcg of Cosyntropin?

It depends on how the vial was mixed. Example: a 5 mg vial plus 2 mL of bacteriostatic water is 2.5 mg/mL, so 250 mcg is 0.1 mL, or 10 units on a U-100 insulin syringe. Change the water and the units change. Use the calculator above with your own vial, and verify with your prescriber.

How long does Cosyntropin stay in your system?

The Peppy catalog lists a half-life of about 15 minutes for Cosyntropin. After roughly five half-lives, about 1.2 hours, most of a single dose has cleared. That is an estimate from the half-life, not a measurement, and individual clearance varies.

Can I track Cosyntropin in Peppy?

Yes. Cosyntropin is one of 123 compounds built into Peppy, with its form, unit and typical frequency prefilled. Add it as a protocol, set your schedule, and Peppy handles the countdown, the log and the reminders (Pro).

Where should I inject Cosyntropin?

Follow your prescriber's instructions. For subcutaneous shots the GLP-1 labels list the abdomen, thigh and upper arm and say to rotate. Peppy's body map has 13 sites, suggests the next one, and shows when each was last used. Read the site rotation guide.

More in Hormonal

Not medical advice. Peppy is a tracking tool, not medical advice. Dose calculations are mathematical conversions only. Always follow your prescriber's instructions and verify every draw-up yourself.

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