MK-677: track every dose and what's still active

Orally active non-peptide ghrelin receptor agonist that elevates GH and IGF-1; researched for muscle wasting and age-related GH decline. In the Peppy catalog, MK-677 is taken by mouth as a capsule, dosed in mg, typically daily, with a listed half-life of about 5 hours.

CategoryGrowth hormone
FormCapsule
Dose unitmg
Typical frequencyDaily
Half-life (catalog)~5 hours
Also known asIbutamoren, MK-0677, L-163, 191

How long MK-677 stays active

Active in your system — MK-677

estimate for daily doses, half-life 5 h
d0d1d2d3d4d5d6d7d8peak0
Half-life ~5 hoursLeft after one daily interval 4%~5 half-lives to clear most of a dose 25 hoursLevels out after about 3 doses

An estimate from the half-life, not a measurement. Individual clearance varies. Peppy shows this curve for each protocol under Active in your system.

MK-677 dose steps in the catalog

MK-677 — catalog dose ladderDose
Step 110 mg
Step 215 mg
Step 320 mg
Step 425 mg

Dose steps as listed in the Peppy catalog so the picker is fast — not a recommendation. Your prescriber sets your dose; Peppy tracks it.

How to track MK-677 in Peppy

  1. Open the Protocols tab, tap + and search for MK-677 (or Ibutamoren). Form, unit and typical frequency are prefilled.
  2. Enter your dose and pick a schedule. Titration step-ups and on/off cycles are available (Pro).
  3. Pick a colour and, for injections, a site rotation order. Peppy suggests the next site each time you log.
  4. On shot day, the Today tab counts down and one tap opens the Log shot sheet with the body map.
  5. Open the protocol to see Active in your system, the half-life curve for what you have logged (Pro).
  6. Log a daily check-in (side effects, feelings, weight) and see it lined up against every dose in Progress.

Track MK-677 in Peppy

Schedule, units, site rotation and reminders. Free on iPhone, no account.

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Frequently asked

How long does MK-677 stay in your system?

The Peppy catalog lists a half-life of about 5 hours for MK-677. After roughly five half-lives, about 25 hours, most of a single dose has cleared. That is an estimate from the half-life, not a measurement, and individual clearance varies.

Can I track MK-677 in Peppy?

Yes. MK-677 is one of 123 compounds built into Peppy, with its form, unit and typical frequency prefilled. Add it as a protocol, set your schedule, and Peppy handles the countdown, the log and the reminders (Pro).

More in Growth hormone

Not medical advice. Peppy is a tracking tool, not medical advice. Dose calculations are mathematical conversions only. Always follow your prescriber's instructions and verify every draw-up yourself.

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