Tesamorelin: units to draw, the daily abdominal shot and site rotation
Tesamorelin is a GHRH analog, FDA-approved as Egrifta to reduce excess abdominal fat in HIV-associated lipodystrophy by stimulating endogenous GH release. The Peppy catalog lists it as a reconstituted vial dosed in mg, daily, with a half-life of about 0.4 hours. Peppy converts vial and water into units, keeps the daily schedule and rotates abdominal sites.
Tesamorelin reconstitution calculator
Tesamorelin reconstitution calculator
Free in the appHow long Tesamorelin stays active
Active in your system — Tesamorelin
estimate for daily doses, half-life 0.4 hAn estimate from the half-life, not a measurement. Individual clearance varies. Peppy shows this curve for each protocol under Active in your system.
Tesamorelin dose steps in the catalog
| Tesamorelin — catalog dose ladder | Dose |
|---|---|
| Step 1 | 1 mg |
| Step 2 | 2 mg |
Dose steps as listed in the Peppy catalog so the picker is fast — not a recommendation. Your prescriber sets your dose; Peppy tracks it.
Tracking tesamorelin: what matters
Tesamorelin is a daily shot, and the label tells you where it goes: the abdomen, rotating sites. That makes rotation the first tracking problem. Seven abdominal shots a week on one side of the navel is how people end up with tender spots, and Peppy's body map has four abdominal quadrants and two flanks, each showing "last used N days ago". The rotation guide has the pattern most people settle on.
The second problem is the units. A tesamorelin reconstitution calculator is standard vial math: a 5 mg vial with 1 mL of water is 5 mg per mL, so 1 mg is 20 units and 2 mg is 40 units. If you use a branded Egrifta kit, the diluent volume and dose are fixed by the kit and the label, and you enter those values so Peppy shows the same number the kit instructions describe. For generic vials, enter the size and the water you add; Peppy recalculates as you type and warns if a draw exceeds 1 mL. See units to draw.
Vial life is short at mg doses: 5 mg at 1 mg a day is five shots. Inventory (Pro) counts vials times doses per vial and shows a run-out date with a running-low alert.
Schedule and cycles
The Peppy catalog lists tesamorelin as daily with a dose ladder of 1 and 2 mg (catalog listing, not a recommendation). The Egrifta SV label describes a once-daily subcutaneous injection. With a half-life the label puts at minutes, the "active in your system" curve is a short daily spike, so the calendar view is more useful than the curve. What people track is simple: the same time every day, and an unbroken run of green dots. Missed and overdue status is computed from the schedule, so a late shot shows as overdue on the Today tab until you log it, then disappears. Any change to timing or dose is your prescriber's call.
How to do this in Peppy
- Open Protocols, tap +, search "tesamorelin" or "Egrifta". The catalog sets vial, mg and daily.
- Enter the mg dose. In the inline Calculator, type vial mg and diluent mL; Peppy shows units per shot.
- Set the time. Under rotation, keep the default order or set a custom one (Pro) that cycles only abdominal sites.
- Add vials in Inventory (Pro).
- Each day, tap the shot on Today, choose the highlighted abdominal site on the body map and log. Add a note if a site was sore.
- Before appointments, use Export (Pro) to hand your prescriber a PDF of every shot and check-in; see export for your doctor.
Track it in Peppy
123 compounds built in, the units math done for you, body-map site rotation and reminders — private on your iPhone.
Free · iPhone · no accountFrequently asked
How many units is 1 mg of tesamorelin?
Example: a 5 mg vial mixed with 1 mL of bacteriostatic water is 5 mg per mL, so 1 mg is 0.2 mL, or 20 units on a U-100 syringe; 2 mg is 40 units. Branded Egrifta kits come with their own diluent and instructions, so follow the kit. Check your mix in Peppy's calculator and verify with your prescriber.
How often is tesamorelin typically scheduled?
The Peppy catalog lists tesamorelin as a daily shot, and the Egrifta SV label describes once-daily injection. Peppy's daily schedule with a fixed time and a reminder (Pro) covers it.
What is tesamorelin's half-life?
The Peppy catalog lists about 0.4 hours (roughly 26 minutes). Egrifta prescribing information reports a mean elimination half-life of 26 minutes for the 1 mg/vial formulation after 14 days of dosing, and 8 minutes for Egrifta SV after a single dose. Either way the "active in your system" chart is a short spike.
Where do you inject tesamorelin?
The Egrifta SV label says to inject into the abdomen and rotate injection sites. Peppy's body map has four abdominal quadrants plus two flanks, and suggests the next one each day. See the rotation guide.
How many units is 1 mg of Tesamorelin?
It depends on how the vial was mixed. Example: a 10 mg vial plus 2 mL of bacteriostatic water is 5 mg/mL, so 1 mg is 0.2 mL, or 20 units on a U-100 insulin syringe. Change the water and the units change. Use the calculator above with your own vial, and verify with your prescriber.
How long does Tesamorelin stay in your system?
The Peppy catalog lists a half-life of about 24 minutes for Tesamorelin. After roughly five half-lives, about 2 hours, most of a single dose has cleared. That is an estimate from the half-life, not a measurement, and individual clearance varies.
Can I track Tesamorelin in Peppy?
Yes. Tesamorelin is one of 123 compounds built into Peppy, with its form, unit and typical frequency prefilled. Add it as a protocol, set your schedule, and Peppy handles the countdown, the log and the reminders (Pro).
Where should I inject Tesamorelin?
Follow your prescriber's instructions. For subcutaneous shots the GLP-1 labels list the abdomen, thigh and upper arm and say to rotate. Peppy's body map has 13 sites, suggests the next one, and shows when each was last used. Read the site rotation guide.
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Not medical advice. Peppy is a tracking tool, not medical advice. Dose calculations are mathematical conversions only. Always follow your prescriber's instructions and verify every draw-up yourself.