Sermorelin: units to draw, nightly timing and a 12-minute half-life
Sermorelin is a GHRH (1-29) analog that stimulates pituitary GH release, historically used clinically for GH deficiency diagnosis and short stature. The Peppy catalog lists it as a reconstituted vial dosed in mcg, typically daily, with a half-life of about 12 minutes. Peppy converts your vial into units per shot, schedules the nightly reminder and rotates sites.
Sermorelin reconstitution calculator
Sermorelin reconstitution calculator
Free in the appHow long Sermorelin stays active
Active in your system — Sermorelin
estimate for daily doses, half-life 0.2 hAn estimate from the half-life, not a measurement. Individual clearance varies. Peppy shows this curve for each protocol under Active in your system.
Sermorelin dose steps in the catalog
| Sermorelin — catalog dose ladder | Dose |
|---|---|
| Step 1 | 200 mcg |
| Step 2 | 300 mcg |
Dose steps as listed in the Peppy catalog so the picker is fast — not a recommendation. Your prescriber sets your dose; Peppy tracks it.
Tracking sermorelin: what matters
Sermorelin is the one compound in this group with a prescribing history, so its numbers are less fuzzy than most. A sermorelin reconstitution calculator still has to work with your vial: 2 mg plus 1 mL of water is 2,000 mcg per mL, so 200 mcg is 10 units and 300 mcg is 15 units. Vials come in several sizes, and a 5 mg vial with 2 mL gives a different answer (8 units for 200 mcg). Peppy keeps the mix on the protocol and prints the units on the card, the reminder and the Log shot sheet.
The half-life, 11 to 12 minutes per the prescribing information, is the reason this is a daily shot rather than a weekly one. It also means the "active in your system" chart looks like a blip; the useful view is the calendar, not the curve. Compare it with CJC-1295 with DAC, which lives at the other end of the scale.
Vial life is the practical concern. A 2 mg vial at 200 mcg a night is 10 shots, so you will reconstitute often. Inventory (Pro) counts vials times doses per vial and projects the run-out date; the inventory guide shows how to handle partial vials.
Schedule and cycles
The Peppy catalog lists sermorelin as daily with a dose ladder of 200 and 300 mcg (catalog listing, not a recommendation). Tracked patterns are a bedtime shot every night, or five nights on with weekends off. Peppy's daily schedule with a fixed time covers the first, and cycles (Pro) auto-skip the off nights so they are never marked missed. Missed and overdue status is computed from the schedule, so pausing a protocol for a holiday and resuming it does not leave a trail of red dots. The cycle tracker guide walks through it. The pattern itself is your prescriber's decision.
How to do this in Peppy
- Open Protocols, tap +, search "sermorelin" (aliases: GRF 1-29, Geref).
- Enter the mcg dose. In the inline Calculator, type vial mg and water mL to get units per shot.
- Set the bedtime and turn on Cycles (Pro) for 5-on/2-off.
- Add vials in Inventory (Pro) so the running-low alert fires before the last shot.
- Each night, log from Today or the Next Shot widget (Pro), tapping the suggested site on the body map.
- Do the daily check-in; sleep is a tracked feeling, and Progress (Pro insights) shows it next to your shots.
Read units to draw if the concentration step is new to you.
Track it in Peppy
123 compounds built in, the units math done for you, body-map site rotation and reminders — private on your iPhone.
Free · iPhone · no accountFrequently asked
How many units is 200 mcg of sermorelin?
Example: a 2 mg vial mixed with 1 mL of bacteriostatic water is 2,000 mcg per mL, so 200 mcg is 0.1 mL, or 10 units on a U-100 syringe; 300 mcg is 15 units. A 5 mg vial with 2 mL is 2,500 mcg/mL, making 200 mcg 8 units. Use Peppy's calculator for your vial and verify with your prescriber.
How often is sermorelin typically scheduled?
The Peppy catalog lists sermorelin as a daily shot; a bedtime shot is what most people log, and some run 5-on/2-off weeks. Peppy handles a fixed nightly time and cycles (Pro). Your prescriber decides the pattern.
What is sermorelin's half-life?
The Peppy catalog lists about 12 minutes (0.2 hours). Sermorelin acetate prescribing information states a half-life of 11 to 12 minutes after intravenous or subcutaneous administration. The "active in your system" chart is therefore a very short spike.
Where do you inject sermorelin?
Subcutaneous sites such as the abdomen and thighs are the ones most people log. Peppy's body map suggests the next site and shows when each was last used. See the rotation guide.
How many units is 200 mcg of Sermorelin?
It depends on how the vial was mixed. Example: a 5 mg vial plus 2 mL of bacteriostatic water is 2.5 mg/mL, so 200 mcg is 0.08 mL, or 8 units on a U-100 insulin syringe. Change the water and the units change. Use the calculator above with your own vial, and verify with your prescriber.
How long does Sermorelin stay in your system?
The Peppy catalog lists a half-life of about 12 minutes for Sermorelin. After roughly five half-lives, about 1 hours, most of a single dose has cleared. That is an estimate from the half-life, not a measurement, and individual clearance varies.
Can I track Sermorelin in Peppy?
Yes. Sermorelin is one of 123 compounds built into Peppy, with its form, unit and typical frequency prefilled. Add it as a protocol, set your schedule, and Peppy handles the countdown, the log and the reminders (Pro).
Where should I inject Sermorelin?
Follow your prescriber's instructions. For subcutaneous shots the GLP-1 labels list the abdomen, thigh and upper arm and say to rotate. Peppy's body map has 13 sites, suggests the next one, and shows when each was last used. Read the site rotation guide.
More in Growth hormone
Not medical advice. Peppy is a tracking tool, not medical advice. Dose calculations are mathematical conversions only. Always follow your prescriber's instructions and verify every draw-up yourself.