Compounded semaglutide: units on the syringe, vial life and what's still active
Compounded semaglutide is pharmacy-compounded semaglutide drawn from a multi-dose vial with an insulin syringe, the same once-weekly GLP-1 agonist as Ozempic and Wegovy, dosed in units per your provider. The Peppy catalog lists it as a vial dosed in units, weekly, half-life about 165 hours. Peppy converts mg to units for your vial's concentration and keeps the shot day.
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Compounded Semaglutide reconstitution calculator
Compounded Semaglutide reconstitution calculator
Free in the appHow long Compounded Semaglutide stays active
Active in your system — Compounded Semaglutide
estimate for weekly doses, half-life 165 hAn estimate from the half-life, not a measurement. Individual clearance varies. Peppy shows this curve for each protocol under Active in your system.
Tracking compounded semaglutide: what matters
A compounded semaglutide tracker has to speak two languages. Your provider talks in milligrams; your syringe is marked in units. The bridge is the concentration on the vial label, usually written as mg per mL. At 2.5 mg/mL, 0.25 mg is 10 units and 1 mg is 40 units; at 5 mg/mL those become 5 and 20. Pharmacies use different concentrations, and a new vial at a new strength is the moment most mistakes happen. Peppy stores the vial's mg and mL on the protocol and prints the units on the card, the reminder and the Log shot sheet, and warns if a draw will not fit a 1 mL syringe. The units guide works through several concentrations.
Most compounded vials come as a liquid, so there is no reconstitution step; you enter the label values as printed. If yours is a powder, enter the vial mg and the water you add instead. Either way the second thing to track is the vial: at 0.5 mg a week a 2.5 mg/mL, 2 mL vial is 10 shots. Inventory (Pro) counts doses left, projects the run-out date and reminds you to reorder. See vial inventory.
The molecule is the same as Ozempic and Wegovy, with a label half-life of about a week. Peppy's "active in your system" curve uses the catalog's 165-hour figure as an estimate, and the daily check-in ties nausea, sulfur burps and weight to each shot.
Schedule and cycles
The Peppy catalog lists compounded semaglutide as weekly with no fixed dose ladder, since the steps are set by your provider. Many people track the same kind of step-ups the branded labels describe; dose step-ups (Pro) let you enter your provider's rungs, in units or mg, with a duration each. Missed and overdue shots are computed from your weekday, never stored, so a late shot shows once. The branded labels' missed-dose rules do not automatically apply to a compounded product; ask your prescriber and see the missed dose guide for how Peppy shows it.
How to do this in Peppy
- Open Protocols, tap +, search "compounded semaglutide". The catalog sets vial, units and weekly.
- In the inline Calculator, type the vial's total mg and mL from the label, then your dose in mg. Peppy shows the units.
- Pick the weekday and time. Add your provider's steps under Dose step-ups (Pro).
- Enter vials in Inventory (Pro).
- On shot day, tap the countdown on Today, choose the suggested site on the body map, confirm the units and log.
- Do the daily check-in; Progress (Pro insights) shows weight and side effects against each shot.
The semaglutide tracker page covers branded and compounded together.
Track it in Peppy
123 compounds built in, the units math done for you, body-map site rotation and reminders — private on your iPhone.
Free · iPhone · no accountFrequently asked
How many units is 0.25 mg of compounded semaglutide?
It depends on the concentration printed on your vial. Example: at 2.5 mg per mL, 0.25 mg is 0.1 mL, or 10 units on a U-100 insulin syringe; 0.5 mg is 20 units and 1 mg is 40 units. At 5 mg/mL every number halves. Enter your vial's mg and mL in Peppy's calculator and verify with your prescriber.
How often is compounded semaglutide taken?
The Peppy catalog lists it as weekly, the same as the branded semaglutide pens. Set the weekday in Peppy and the countdown, reminder (Pro) and widget (Pro) follow it.
What is the half-life of compounded semaglutide?
It is the same molecule as Ozempic and Wegovy, whose labels report an elimination half-life of approximately one week. The Peppy catalog lists 165 hours and uses it for the "active in your system" estimate.
Why is my compounded semaglutide tracker in units instead of mg?
Because you draw it with an insulin syringe, which is marked in units. A unit is 0.01 mL; the mg it contains depends on the vial's concentration. Peppy stores both so the log shows units and mg side by side. See the units guide.
Where do you inject compounded semaglutide?
Most people log the abdomen, thighs or upper arms, the same sites the branded pen labels list. Peppy's body map suggests the next site. See the rotation guide.
How many units is 0.25 mg of Compounded Semaglutide?
It depends on how the vial was mixed. Example: a 5 mg vial plus 2 mL of bacteriostatic water is 2.5 mg/mL, so 0.25 mg is 0.1 mL, or 10 units on a U-100 insulin syringe. Change the water and the units change. Use the calculator above with your own vial, and verify with your prescriber.
How long does Compounded Semaglutide stay in your system?
The Peppy catalog lists a half-life of about 6.9 days for Compounded Semaglutide. After roughly five half-lives, about 4.9 weeks, most of a single dose has cleared. That is an estimate from the half-life, not a measurement, and individual clearance varies.
Can I track Compounded Semaglutide in Peppy?
Yes. Compounded Semaglutide is one of 123 compounds built into Peppy, with its form, unit and typical frequency prefilled. Add it as a protocol, set your schedule, and Peppy handles the countdown, the log and the reminders (Pro).
Where should I inject Compounded Semaglutide?
Follow your prescriber's instructions. For subcutaneous shots the GLP-1 labels list the abdomen, thigh and upper arm and say to rotate. Peppy's body map has 13 sites, suggests the next one, and shows when each was last used. Read the site rotation guide.
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Not medical advice. Peppy is a tracking tool, not medical advice. Dose calculations are mathematical conversions only. Always follow your prescriber's instructions and verify every draw-up yourself.